Patricia C. Dos Santos

Dr. Patricia Dos Santos

Endowed Wake Forest Professor

Department Associate Chair

Office: Wake Downtown, Rm. 2818
Phone: (336) 702-1944
Emaildossanpc@wfu.edu

Education

B.S., 1999, Universidade Federal do Rio Grande do Sul (Porto Alegre, Brazil)
Ph.D., 2004, Virginia Tech
Postdoctoral Associate, 2005-2008, Virginia Tech (Dennis Dean)

Research Description

Iron and sulfur atoms can form chemical structures of biological importance named [Fe-S] clusters.  The importance of Fe-S clusters is intimately associated with the essential role of Fe-S proteins in a wide range of life sustaining processes including respiration, carbon metabolism, photosynthesis and nitrogen fixation.  These chemical structures are organized in fundamental units of [2Fe-2S] and [4Fe-4S] clusters, or multimers, or fragments of these units.  Although [Fe-S] clusters can be formed in vitro from their toxic individual components, almost all forms of life have developed specialized machineries dedicated to the assembly of these metal-centers.  Our research group is interested in understanding the biochemical formation of [Fe-S] clusters in Gram-positive bacteria.

Publications

View My Publications

Awards and Accomplishments

2020                URECA Faculty Award for Excellence in Mentorship in Research

2018-2021       Robert & Debra Lee Faculty Fellowship

2018-2019       Freiburg Institute for Advanced Sciences Fellow

2013-2016       Z. Smith Reynolds Foundation Faculty Fellowship

2013                Faculty Excellence in Research Award, Wake Forest University

2011                NSF CAREER Award

2010                Outstanding Recent Alumna of the College of Agriculture and Life Sciences, Virginia Tech